Skip to contents

Gene expression of 108 CCLE cell lines from 5 different pediatric cancers.

Usage

data("pedcan_expression", package = "scimo")

Format

A tibble with columns:

cell_line

Cell line name.

sex

One of Male, Female or Unknown.

event

One of Primary, Metastasis or Unknown.

disease

One of Neuroblastoma, Ewing Sarcoma, Rhabdomyosarcoma, Embryonal Tumor or Osteosarcoma.

other columns

Expression of the gene, given in log2(TPM + 1).

Source

This dataset is generated from DepMap Public 23Q4 primary files. https://depmap.org/portal/download/all/.

Examples

data("pedcan_expression", package = "scimo")
pedcan_expression
#> # A tibble: 108 × 19,197
#>    cell_line sex   event disease  A1BG   A1CF   A2M  A2ML1 A3GALT2 A4GALT  A4GNT
#>    <chr>     <chr> <chr> <chr>   <dbl>  <dbl> <dbl>  <dbl>   <dbl>  <dbl>  <dbl>
#>  1 143B      Fema… Prim… Osteos…  3.02 0.0566 2.78  0       0       2.13  0     
#>  2 A-673     Fema… Prim… Ewing …  4.87 0      2.00  3.19    0.0841  4.62  0.189 
#>  3 BT-12     Fema… Prim… Embryo…  3.52 0.0286 0.111 0       0       2.32  0.0704
#>  4 BT-16     Male  Unkn… Embryo…  3.51 0      0.433 0.0144  0       1.54  0.0144
#>  5 C396      Male  Meta… Osteos…  4.59 0      0.956 0       0       5.10  0     
#>  6 CADO-ES1  Fema… Meta… Ewing …  5.89 0      0.614 0.379   0.0704  6.60  0.151 
#>  7 CAL-72    Male  Prim… Osteos…  4.35 0.0426 0.333 0       0       0.614 0     
#>  8 CBAGPN    Fema… Prim… Ewing …  4.87 0.0976 1.33  0.111   0       0.722 0.0704
#>  9 CHLA-06   Fema… Unkn… Embryo…  5.05 0      0.124 0       0       0.848 0.138 
#> 10 CHLA-10   Fema… Unkn… Ewing …  5.05 0.0144 0.949 1.73    0.0704  0.506 0.0704
#> # ℹ 98 more rows
#> # ℹ 19,186 more variables: AAAS <dbl>, AACS <dbl>, AADAC <dbl>, AADACL2 <dbl>,
#> #   AADACL3 <dbl>, AADACL4 <dbl>, AADAT <dbl>, AAGAB <dbl>, AAK1 <dbl>,
#> #   AAMDC <dbl>, AAMP <dbl>, AANAT <dbl>, AAR2 <dbl>, AARD <dbl>, AARS1 <dbl>,
#> #   AARS2 <dbl>, AARSD1 <dbl>, AASDH <dbl>, AASDHPPT <dbl>, AASS <dbl>,
#> #   AATF <dbl>, AATK <dbl>, ABAT <dbl>, ABCA1 <dbl>, ABCA10 <dbl>,
#> #   ABCA12 <dbl>, ABCA13 <dbl>, ABCA2 <dbl>, ABCA3 <dbl>, ABCA4 <dbl>, …